Publications

RESEARCH PAPERS:

  • Krchniakova M, Skoda J, Neradil J, Chlapek P, Veselska R: Repurposing tyrosine kinase inhibitors to overcome multidrug resistance in cancer: a focus on transporters and lysosomal sequestration. International Journal of Molecular Sciences 21, Art. No. 3157, 2020.
  • Mikulenkova E, Neradil J, Vymazal O, Skoda J, Veselska R: NANOG/NANOGP8 Localizes at the Centrosome and is Spatiotemporally Associated with Centriole Maturation. Cells 9, Art. No. 692, 2020.
  • Skoda J, Neradil J, Staniczkova Zambo I, Nunukova A, Macsek P, Borankova K, Dobrotkova V, Nemec P, Sterba J, Veselska R: Serial xenotransplantation in NSG mice promotes a hybrid epithelial/mesenchymal gene expression signature and stemness in rhabdomyosarcoma cells. Cancers 12, Art. No. 196, 2020.
  • Polaskova K, Merta T, Martincekova A, Zapletalova D, Kyr M, Mazanek P, Krenova Z, Mudry P, Tuma J, Skotakova J, Cervinkova I, Valik D, Zdrazilova Dubska L, Noskova H, Pal K, Slaby O, Fabian P, Kozakova S, Neradil J, Veselska R, Kanderova V, Hrusak O, Freiberger T, Klement GL, Sterba J: Comprehensive molecular profiling for relapsed/refractory pediatric Burkitt lymphomas – retrospective analysis of three real life clinical cases – addressing issues on randomization and customization at the bedside. Frontiers in Oncology 9, Art. No. 1531, 2019.
  • Gojo J, Pavelka Z, Zapletalova D, Schmook MT, Mayr L, Madlener S, Kyr M, Vejmelkova K, Smrcka M, Czech T, Dorfer C, Skotakova J, Azizi AA, Chocholous M, Reisinger D, Lastovicka D, Valik D, Haberler C, Peyrl A, Noskova H, Pal K, Jezova M, Veselska R, Kozakova S, Slaby O, Slavc I, Sterba J: Personalized Treatment of H3K27M-Mutant Pediatric Diffuse Gliomas Provides Improved Therapeutic Opportunities. Frontiers in Oncology 9, Art. No. 1436, 2019.
  • Veselska R, Jezova M, Kyr M, Mazanek P, Chlapek P, Dobrotkova V, Sterba J: Comparative Analysis of Putative Prognostic and Predictive Markers in Neuroblastomas: High Expression of PBX1 Is Associated with a Poor Response to Induction Therapy. Frontiers in Oncology 9, Art. No. 1221, 2019.
  • Neradil J, Kyr M, Polaskova K, Kren L, Macigova P, Skoda J, Sterba J, Veselska R: Phospho-Protein Arrays as Effective Tools for Screening Possible Targets for Kinase Inhibitors and Their Use in Precision Pediatric Oncology. Frontiers in Oncology 9, Art. No. 930, 2019.
  • Kyr M, Polaskova K, Kuttnerova Z, Merta T, Neradil J, Berkovcova J, Horky O, Jezova M, Veselska R, Klement GL, Valik D, Sterba J: Individualization of Treatment Improves the Survival of Children with High-Risk Solid Tumors: Comparative Patient Series Analysis in a Real-Life Scenario. Frontiers in Oncology 9, Art. No. 644, 2019.
  • Dobrotkova V, Chlapek P, Jezova M, Adamkova K, Mazanek P, Sterba J, Veselska R: Prediction of neuroblastoma cell response to treatment with natural or synthetic retinoids using selected protein biomarkers. PLoS ONE 14, Art. No. e0218269, 2019.
  • Gomes S, Raimundo L, Soares J, Loureiro JB, Leão M, Ramos H, Monteiro MN, Lemos A, Moreira J, Pinto M, Chlapek P, Veselska R, Sousa E, Saraiva L: New inhibitor of the TAp73 interaction with MDM2 and mutant p53 with promising antitumor activity against neuroblastoma. Cancer Letters 446, 90-102, 2019.
  • Skoda J, Borankova K, Jansson PJ, Huang ML, Veselska R, Richardson DR: Pharmacological targeting of mitochondria in cancer stem cells: An ancient organelle at the crossroad of novel anti-cancer therapies. Pharmacological Research 139, 298-313, 2018.
  • Dobrotkova V, Chlapek P, Mazanek P, Sterba J, Veselska R: Traffic lights for retinoids in oncology: molecular markers of retinoid resistance and sensitivity and their use in the management of cancer differentiation therapy. BMC Cancer 18, Art. No. 1059, 2018.
  • Sramek M, Neradil J, Macigova P, Mudry P, Polaskova K, Slaby O, Noskova H, Sterba J, Veselska R: Effects of sunitinib and other kinase inhibitors on cells harboring a PDGFRB mutation associated with infantile myofibromatosis. International Journal of Molecular Sciences 19, Art. No. 2599, 2018.
  • Skoda J, Veselska R: Cancer stem cells in sarcomas: Getting to the stemness core. Biochimica et Biophysica Acta – General Subjects 1862, 2134-2139, 2018.
  • Chlapek P, Slavikova V, Mazanek P, Sterba J, Veselska R: Why differentiation therapy sometimes fails: molecular mechanisms of resistance to retinoids. International Journal of Molecular Sciences 19, Art. No. 132, 2018.
  • Chlapek P, Zitterbart K, Kren L, Filipova L, Sterba J, Veselska R: Uniformity under in vitro conditions: Changes in the phenotype of cancer cell lines derived from different medulloblastoma subgroups. PLoS ONE 12, Art. No. e0172552, 2017.
  • Mudry P, Slaby O, Neradil J, Soukalova J, Melicharkova K, Rohleder O, Jezova M, Seehofnerova A, Michu E, Veselska R, Sterba J: Case report: Rapid and durable response to PDGFR targeted therapy in a child with refractory multiple infantile myofibromatosis and a heterozygous germline mutation of the PDGFRB gene. BMC Cancer 17, Art. No. 119, 2017.
  • Sramek M, Neradil J, Veselska R: Much more than you expected: The non-DHFR-mediated effects of methotrexate. Biochimica et Biophysica Acta – General Subjects 1861, 499-503, 2017.
  • Skoda J, Hermanova M, Loja T, Nemec P, Neradil J, Karasek P, Veselska R: Co-expression of cancer stem cell markers corresponds to a pro-tumorigenic expression profile in pancreatic adenocarcinoma. PLoS ONE 11, Art. No. e0159255, 2016.
  • Zambo I, Hermanova M, Zapletalova D, Skoda J, Mudry P, Kyr M, Zitterbart K, Sterba J, Veselska R: Expression of nestin, CD133 and ABCG2 in relation to the clinical outcome in pediatric sarcomas. Cancer Biomarkers 17, 107-116, 2016.
  • Skoda J, Nunukova A, Loja T, Zambo I, Neradil J, Mudry P, Zitterbart K, Hermanova M, Hampl A, Sterba J, Veselska R: Cancer stem cell markers in pediatric sarcomas: Sox2 is associated with tumorigenicity in immunodeficient mice. Tumor Biology 37, 9535-9548, 2016.
  • Sramek M, Neradil J, Sterba J, Veselska R: Non-DHFR-mediated effects of methotrexate in osteosarcoma cell lines: epigenetic alterations and enhanced cell differentiation. Cancer Cell International 16, Art. No. 14, 2016.
  • Melicharkova K, Neradil J, Mudry P, Zitterbart K, Obermannova R, Skotakova J, Veselska R, Sterba J: Profile of activation of tyrosine kinases and MAP kinases in therapy of Maffucci syndrome. Klinicka Onkologie 28 (Suppl 2), 2S47-2S51, 2015.
  • Mikulenkova E, Neradil J, Zitterbart K, Sterba J, Veselska R: Overexpression of the ∆Np73 isoform is associated with centrosome amplification in brain tumor cell lines. Tumor Biology 36, 7483-7491, 2015.
  • Neradil J, Veselska R: Nestin as a marker of cancer stem cells. Cancer Science 106, 803-811, 2015 (+ July 2015 Cover Image).
  • Nunukova A, Neradil J, Skoda J, Jaros J, Hampl A, Sterba J, Veselska R: Atypical nuclear localization of cd133 plasma membrane glycoprotein in rhabdomyosarcoma cell lines. International Journal of Molecular Medicine 36, 65-72, 2015.
  • Neradil J, Pavlasova G, Sramek M, Kyr M, Veselska R, Sterba J: DHFR-mediated effects of methotrexate in medulloblastoma and osteosarcoma cells: the same outcome of treatment with different doses in sensitive cell lines. Oncology Reports 33, 2169-2175, 2014.
  • Chlapek P, Neradil J, Redova M, Zitterbart K, Sterba J, Veselska R: The ATRA-induced differentiation of medulloblastoma cells is enhanced with LOX/COX inhibitors: an analysis of gene expression. Cancer Cell International 14, Art. No. 51, 2014.
  • Krzyzankova M, Chovanova S, Chlapek P, Radsetoulal M, Neradil J, Zitterbart K, Sterba J, Veselska R: LOX/COX inhibitors enhance the antineoplastic effects of all-trans retinoic acid in osteosarcoma cell lines. Tumor Biology 35, 7617-7627, 2014.
  • Skoda J, Neradil J, Veselska R: Functional assays for detection of cancer stem cells. Klinicka Onkologie 27 (Suppl 1), 42-47, 2014.
  • Chlapek P, Chovanova S, Slavikova V, Veselska R: Tumor microenvironment - possibilities of the research under in vitro conditions. Klinicka Onkologie 27 (Suppl 1), 48-52, 2014.
  • Skoda J, Neradil J, Zitterbart K, Sterba J, Veselska R: EGFR signaling in the HGG-02 glioblastoma cell line with an unusual loss of EGFR gene copy. Oncology Reports 31, 480-487, 2014.
  • Veselska R, Neradil J, Nekulova M, Dobrucka L, Vojtesek B, Sterba J, Zitterbart K: Intracellular distribution of the deltaNp73 protein isoform in medulloblastoma cells: a study with newly generated rabbit polyclonal antibodies. Histology and Histopathology 28, 913-924, 2013.
  • Veselska R, Skoda J, Neradil J: Detection of cancer stem cell markers in sarcomas. Klinicka Onkologie 25 (Suppl 2), 2S16–2S20, 2012.
  • Neradil J, Pavlasova G, Veselska R: New mechanisms for an old drug: DHFR- and non-DHFR-mediated effects of methotrexate in cancer cells. Klinicka Onkologie 25 (Suppl 2), 2S87-2S92, 2012.
  • Zambo I, Hermanova M, Adamkova Krakorova D, Mudry P, Zitterbart K, Kyr M, Vesely K, Sterba J, Veselska R: Nestin expression in high-grade osteosarcomas and its clinical significance. Oncology Reports 27, 1592-1598, 2012.
  • Lenz J, Karasek P, Jarkovsky J, Muckova K, Dite P, Kala Z, Veselska R, Hermanova M: Clinicopathological correlations of nestin expression in surgically resectable pancreatic cancer including an analysis of perineural invasion. Journal of Gastrointestinal and Liver Diseases 20, 389-396, 2011.
  • Sana J, Zambo I, Skoda J, Neradil J, Chlapek P, Hermanova M, Mudry P, Vasikova A, Zitterbart K, Hampl A, Sterba J, Veselska R: CD133 expression and identification of CD133/nestin positive cells in rhabdomyosarcomas and rhabdomyosarcoma cell lines. Analytical Cellular Pathology 34, 303-318, 2011.
  • Krupkova Jr O, Loja T, Redova M, Neradil J, Zitterbart K, Sterba J, Veselska R: Analysis of nuclear nestin localization in cell lines derived from neurogenic tumors. Tumor Biology 32, 631-639, 2011.
  • Zitterbart K, Filkova H, Tomasikova L, Necesalova E, Zambo I, Kantorova D, Slamova I, Vranova V, Zezulkova D, Pesakova M, Pavelka Z, Veselska R, Kuglik P, Sterba J: Low-level copy number changes of MYC genes have a prognostic impact in medulloblastoma. Journal of Neurooncology 102, 25-33, 2011.
  • Nekulova M, Zitterbart K, Sterba J, Veselska R: Analysis of the intracellular localization of p73 N-terminal protein isoforms TAp73 and delta-Np73 in medulloblastoma cell lines. Journal of Molecular Histology 41, 267-275, 2010.
  • Chlapek P, Redova M, Zitterbart K, Hermanova M, Sterba J, Veselska R: Enhancement of ATRA-induced differentiation of neuroblastoma cell lines with LOX/COX inhibitors: an expression profiling study. Journal of Experimental & Clinical Cancer Research 29, Art. No. 45, 2010.
  • Krupkova Jr O, Loja T, Zambo I, Veselska R: Nestin expression in human tumors and tumor cell lines. Neoplasma 57, 291-298, 2010.
  • Veselska R, Skoda J, Loja T, Zitterbart K, Pavelka Z, Smardova J, Valaskova I, Hermanova M, Sterba J: An unusual loss of EGFR gene copy in glioblastoma multiforme in a child: a case report and analysis of a successfully derived HGG-02 cell line. Child’s Nervous System 26, 841-846, 2010.
  • Redova M, Chlapek P, Loja T, Zitterbart K, Hermanova M, Sterba J, Veselska R: Influence of LOX/COX inhibitors on cell differentiation induced by all-trans retinoic acid in neuroblastoma cell lines. International Journal of Molecular Medicine 25, 271-280, 2010.
  • Loja T, Chlapek P, Kuglik P, Pesakova M, Oltova A, Cejpek P, Veselska R: Characterization of a glioblastoma cell line showing CD133 positivity and both cytoplasmic and nuclear localization of nestin. Oncology Reports 21, 119-128, 2009.
  • Veselska R, Hermanova M, Loja T, Chlapek P, Zambo I, Vesely K, Zitterbart K, Sterba J: Nestin expression in osteosarcomas and derivation of nestin/CD133 positive osteosarcoma cell lines. BMC Cancer 8, Art. No. 300, 2008.
  • Mazanek P, Bajciova V, Sterba J, Kuglik P, Veselska R: Novinky v diagnostice a lecbe neuroblastomu. Onkologia 4, 1-5, 2008
  • Necesalova E, Vranova V, Kuglik P, Cejpek P, Jarosova M, Pesakova M, Relichova J, Veselska R: Incidence of the main genetic markers in glioblastoma multiforme is independent of tumor topology. Neoplasma 54, 212-218, 2007.
  • Vranova V, Necesalova E, Kuglik P, Cejpek P, Pesakova M, Budinska E, Relichova J, Veselska R: Screening of genomic imbalances in glioblastoma multiforme using high-resolution comparative genomic hybridization. Oncology Reports 17, 457-464, 2007.
  • Loja T, Kuglik P, Oltova A, Smuharova P, Zitterbart K, Bajciova V, Veselska R: The optimization of sample treatment for spectral karyotyping with application for human tumour cells. Cytogenetics and Genome Research 116, 186-193, 2007
  • Veselska R: Ethics of research on human embryonic stem cell lines. In: Deltas C, Kalokairinou EM, Rogge S (eds.): Progress in Science and the Danger of Hubris – Genetics, Transplantation, Stem Cell Research, pp. 101-108. Muenster: Waxmann Verlag, 2006.
  • Veselska R, Kuglik P, Cejpek P, Svachova H, Neradil J, Loja T, Relichova J: Nestin expression in cell lines derived from glioblastoma multiforme. BMC Cancer 6, Art. No. 32, 2006.
  • Necesalova E, Kuglik P, Cejpek P, Veselska R, Vranova V, Pesakova M, Relichova J: Studium polyzomie chromozomu 7, monozomie chromozomu 10, amplifikace genu EGFR a delece genu p53 u multiformniho glioblastomu pomoci metody fluorescencni in situ hybridizace (FISH). Klinicka Onkologie 19, 9-14, 2006.
  • Neradil J, Veselska R, Svoboda A: The role of actin in the apoptotic cell death of P19 embryonal carcinoma cells. International Journal of Oncology 27, 1013-1021, 2005.
  • Veselska R, Zitterbart K, Auer J, Neradil J: Differentiation of HL-60 myeloid leukemia cells induced by all-trans retinoic acid is enhanced in combination with caffeic acid. International Journal of Molecular Medicine 14, 305-310, 2004.
  • Veselska R, Kure J: Pravni a eticke aspekty zpracovani klinickych dat. Klinicka Onkologie Suppl 2004, 37-38, 2004.
  • Veselska R, Zitterbart K, Jelinkova S, Neradil J, Svoboda A: Specific cytoskeleton changes during apoptosis accompanying induced differentiation of HL-60 myeloid leukemia cells. Oncology Reports 10, 1049-1058, 2003.
  • Neradil J, Veselska R, Slanina J: UVC-protective effect of caffeic acid on the normal and transformed human skin cells in vitro. Folia Biologica 49, 197-202, 2003.
  • Koutna M, Janisch R, Veselska R: Effects of low-power laser irradiation on cell proliferation. Scripta Medica 76, 163-172, 2003.
  • Veselska R, Janisch R: Reaction of the skin fibroblast cytoskeleton to micromanipulation interventions. Journal of Structural Biology 136, 110-118, 2001.
  • Veselska R, Janisch R: Cortical actin cytoskeleton in the human oocytes: A comparison with the mouse oocytes. Scripta Medica 74, 265-272, 2001.
  • Zitterbart K, Veselska R: Effect of retinoic acid on the actin cytoskeleton in HL-60 cells. Neoplasma 48, 456-461, 2001.
  • Veselska R, Janisch R: The effect of UV irradiation on changes in cytoskeleton and viability of mouse fibroblasts L929 cell line. Scripta Medica 73, 393-408, 2000.
  • Halackova Z, Veselska R: Cytotoxicita endodontickych sealeru. Ceska stomatologie 99, 101-106, 1999.
  • Chroust K, Kuglik P, Relichova J, Holoubek I, Caslavsky J, Veselska R, Ryskova M, Benedik J: Drosophila melanogaster, Vicia faba and Arabidopsis thaliana short-term bioassays in genotoxicity evaluation air and soil samples from sites surrounding two industrial factories in the Czech Republic. Folia Biologica 43, 71-78, 1997.
  • Veselska R, Kuglik P, Relichova J: The influence of incorporated bromodeoxyuridine on mutagenicity testing by sister chromatid exchange induction in Vicia faba root-tip cells. Biologia Plantarum 37, 9-14, 1995.
  • Kuglik P, Veselska R: The use of micronucleus test to characterise adaptation of Vicia faba root tip cells to gamma-radiation. Biologia Plantarum 36, 215-220, 1994.
  • Kuglik P, Veselska R: Characterization of a cytogenetic adaptive response induced by gamma-radiation in Vicia faba root tip cells. Folia Biologica 38, 14-22, 1992.
  • Kuglik P, Slotova J, Dobricka R, Karpfel Z: Vicia faba chromosome damage induced by low doses of gamma radiation. Biologia Plantarum 32, 113-118, 1990.

TEXTBOOKS AND OTHER PUBLICATIONS:

  • Veselska R: Eticke aspekty molekularni mediciny [Ethical aspects of molecular medicine]. In: Slaby O (ed.): Molekularni medicina, Galen, Praha 2015. ISBN 9788074921216.
  • Kure J, Halamkova J, Kintrova K, Mikoskova M, Pavlik M, Slama O, Veselska R, Vysocanova P, Zvonicek V: Kapitoly z lekarske etiky. Multimedialni podpora vyuky klinickych a zdravotnickych oboru: Portal Lekarske fakulty Masarykovy univerzity, 2011.  ISSN 1801-6103.
  • Snustad DP, Simmons MJ (Translators: Relichova J, Doskar J, Fajkus J, Horin P, Knoll A, Kuglik P, Smarda J, Smardova J, Veselska R, Vyskot B): Genetika (Czech translation of the textbook). Brno: Masaryk University, MUNI Press 2009. ISBN 978-80-210-4852-2.
  • Veselska R, Smajs D, Neradil J, Matejkova P, Slaninova I, Svoboda A, Kopecka M, Gabriel M, Smarda J, Janisch R: Prakticka cviceni z biologie. Protokoly – cast II. Brno: Masarykova univerzita, 2005. ISBN 80-210-3644-3.
  • Veselska R, Gabriel M, Janisch R, Kopecka M, Neradil J, Slaninova I, Svoboda A, Smajs D, Smarda J: Prakticka cviceni z biologie. Protokoly – cast I. Brno: Masarykova univerzita, 2004. ISBN 80-210-3487-4.
  • Veselska R, Kure J (eds.): Transplantacni medicina: soucasnost a perspektivy. Sbornik k interdisciplinarni konferenci. Brno: Masarykova univerzita, 2001. ISBN 80-210-2714-2.
  • Kopecka M, Gabriel M, Svoboda A, Janisch R, Slaninova I, Veselska R, Smarda J, Chumchalova J, Holubarova A: Lekarska biologie. Cast druha – Genetika. Brno, Masarykova univerzita, 2001. ISBN 80-210-2670-7.
  • Veselska R, Kure J (eds.): Lidsky genom: vedeni, moznosti, souvislosti. Sbornik k interdisciplinarni konferenci. Brno: Masarykova univerzita, 2000. ISBN 80-210-2447-X.
  • Svoboda A, Gabriel M, Kopecka M, Janisch R, Slaninova I, Smajs D, Smarda J, Veselska R: Prakticka cviceni z biologie. Protokoly – cast I. Brno: Masarykova univerzita, 1998. ISBN 80-210-1852-6.