Publications

RESEARCH PAPERS:

  • Neradil J, Kyr M, Polaskova K, Kren L, Macigova P, Skoda J, Sterba J, Veselska R: Phospho-Protein Arrays as Effective Tools for Screening Possible Targets for Kinase Inhibitors and Their Use in Precision Pediatric Oncology. Frontiers in Oncology 2019 accepted.
  • Kyr M, Polaskova K, Kuttnerova Z, Merta T, Neradil J, Berkovcova J, Horky O, Jezova M, Veselska R, Klement GL, Valik D, Sterba J: Individualization of Treatment Improves the Survival of Children with High-Risk Solid Tumors: Comparative Patient Series Analysis in a Real-Life Scenario. Frontiers in Oncology 9, Art. No. 644, 2019.
  • Dobrotkova V, Chlapek P, Jezova M, Adamkova K, Mazanek P, Sterba J, Veselska R: Prediction of neuroblastoma cell response to treatment with natural or synthetic retinoids using selected protein biomarkers. PLoS ONE 14, Art. No. e0218269, 2019.
  • Gomes S, Raimundo L, Soares J, Loureiro JB, Leão M, Ramos H, Monteiro MN, Lemos A, Moreira J, Pinto M, Chlapek P, Veselska R, Sousa E, Saraiva L: New inhibitor of the TAp73 interaction with MDM2 and mutant p53 with promising antitumor activity against neuroblastoma. Cancer Letters 446, 90-102, 2019.
  • Skoda J, Borankova K, Jansson PJ, Huang ML, Veselska R, Richardson DR: Pharmacological targeting of mitochondria in cancer stem cells: An ancient organelle at the crossroad of novel anti-cancer therapies. Pharmacological Research 139, 298-313, 2018.
  • Dobrotkova V, Chlapek P, Mazanek P, Sterba J, Veselska R: Traffic lights for retinoids in oncology: molecular markers of retinoid resistance and sensitivity and their use in the management of cancer differentiation therapy. BMC Cancer 18, Art. No. 1059, 2018.
  • Sramek M, Neradil J, Macigova P, Mudry P, Polaskova K, Slaby O, Noskova H, Sterba J, Veselska R: Effects of sunitinib and other kinase inhibitors on cells harboring a PDGFRB mutation associated with infantile myofibromatosis. International Journal of Molecular Sciences 19, Art. No. E2599, 2018.
  • Skoda J, Veselska R: Cancer stem cells in sarcomas: Getting to the stemness core. Biochimica et Biophysica Acta – General Subjects 1862, 2134-2139, 2018.
  • Chlapek P, Slavikova V, Mazanek P, Sterba J, Veselska R: Why differentiation therapy sometimes fails: molecular mechanisms of resistance to retinoids. International Journal of Molecular Sciences 19, Art. No. E132, 2018.
  • Chlapek P, Zitterbart K, Kren L, Filipova L, Sterba J, Veselska R: Uniformity under in vitro conditions: Changes in the phenotype of cancer cell lines derived from different medulloblastoma subgroups. PLoS ONE 12, Art. No. e0172552, 2017.
  • Mudry P, Slaby O, Neradil J, Soukalova J, Melicharkova K, Rohleder O, Jezova M, Seehofnerova A, Michu E, Veselska R, Sterba J: Case report: Rapid and durable response to PDGFR targeted therapy in a child with refractory multiple infantile myofibromatosis and a heterozygous germline mutation of the PDGFRB gene. BMC Cancer 17, Art. No. 119, 2017.
  • Sramek M, Neradil J, Veselska R: Much more than you expected: The non-DHFR-mediated effects of methotrexate. Biochimica et Biophysica Acta – General Subjects 1861, 499-503, 2017.
  • Skoda J, Hermanova M, Loja T, Nemec P, Neradil J, Karasek P, Veselska R: Co-expression of cancer stem cell markers corresponds to a pro-tumorigenic expression profile in pancreatic adenocarcinoma. PLoS ONE 11, Art. No. e0159255, 2016.
  • Zambo I, Hermanova M, Zapletalova D, Skoda J, Mudry P, Kyr M, Zitterbart K, Sterba J, Veselska R: Expression of nestin, CD133 and ABCG2 in relation to the clinical outcome in pediatric sarcomas. Cancer Biomarkers 17, 107-116, 2016.
  • Skoda J, Nunukova A, Loja T, Zambo I, Neradil J, Mudry P, Zitterbart K, Hermanova M, Hampl A, Sterba J, Veselska R: Cancer stem cell markers in pediatric sarcomas: Sox2 is associated with tumorigenicity in immunodeficient mice. Tumor Biology 37, 9535-9548, 2016.
  • Sramek M, Neradil J, Sterba J, Veselska R: Non-DHFR-mediated effects of methotrexate in osteosarcoma cell lines: epigenetic alterations and enhanced cell differentiation. Cancer Cell International 16, Art. No. 14, 2016.
  • Melicharkova K, Neradil J, Mudry P, Zitterbart K, Obermannova R, Skotakova J, Veselska R, Sterba J: Profile of activation of tyrosine kinases and MAP kinases in therapy of Maffucci syndrome. Klinicka Onkologie 28 (Suppl 2), 2S47-2S51, 2015.
  • Mikulenkova E, Neradil J, Zitterbart K, Sterba J, Veselska R: Overexpression of the ∆Np73 isoform is associated with centrosome amplification in brain tumor cell lines. Tumor Biology 36, 7483-7491, 2015.
  • Neradil J, Veselska R: Nestin as a marker of cancer stem cells. Cancer Science 106, 803-811, 2015 (+ July 2015 Cover Image).
  • Nunukova A, Neradil J, Skoda J, Jaros J, Hampl A, Sterba J, Veselska R: Atypical nuclear localization of cd133 plasma membrane glycoprotein in rhabdomyosarcoma cell lines. International Journal of Molecular Medicine 36, 65-72, 2015.
  • Neradil J, Pavlasova G, Sramek M, Kyr M, Veselska R, Sterba J: DHFR-mediated effects of methotrexate in medulloblastoma and osteosarcoma cells: the same outcome of treatment with different doses in sensitive cell lines. Oncology Reports 33, 2169-2175, 2014.
  • Chlapek P, Neradil J, Redova M, Zitterbart K, Sterba J, Veselska R: The ATRA-induced differentiation of medulloblastoma cells is enhanced with LOX/COX inhibitors: an analysis of gene expression. Cancer Cell International 14, Art. No. 51, 2014.
  • Krzyzankova M, Chovanova S, Chlapek P, Radsetoulal M, Neradil J, Zitterbart K, Sterba J, Veselska R: LOX/COX inhibitors enhance the antineoplastic effects of all-trans retinoic acid in osteosarcoma cell lines. Tumor Biology 35, 7617-7627, 2014.
  • Skoda J, Neradil J, Veselska R: Functional assays for detection of cancer stem cells. Klinicka Onkologie 27 (Suppl 1), 42-47, 2014.
  • Chlapek P, Chovanova S, Slavikova V, Veselska R: Tumor microenvironment - possibilities of the research under in vitro conditions. Klinicka Onkologie 27 (Suppl 1), 48-52, 2014.
  • Skoda J, Neradil J, Zitterbart K, Sterba J, Veselska R: EGFR signaling in the HGG-02 glioblastoma cell line with an unusual loss of EGFR gene copy. Oncology Reports 31, 480-487, 2014.
  • Veselska R, Neradil J, Nekulova M, Dobrucka L, Vojtesek B, Sterba J, Zitterbart K: Intracellular distribution of the deltaNp73 protein isoform in medulloblastoma cells: a study with newly generated rabbit polyclonal antibodies. Histology and Histopathology 28, 913-924, 2013.
  • Veselska R, Skoda J, Neradil J: Detection of cancer stem cell markers in sarcomas. Klinicka Onkologie 25 (Suppl 2), 2S16–2S20, 2012.
  • Neradil J, Pavlasova G, Veselska R: New mechanisms for an old drug: DHFR- and non-DHFR-mediated effects of methotrexate in cancer cells. Klinicka Onkologie 25 (Suppl 2), 2S87-2S92, 2012.
  • Zambo I, Hermanova M, Adamkova Krakorova D, Mudry P, Zitterbart K, Kyr M, Vesely K, Sterba J, Veselska R: Nestin expression in high-grade osteosarcomas and its clinical significance. Oncology Reports 27, 1592-1598, 2012.
  • Lenz J, Karasek P, Jarkovsky J, Muckova K, Dite P, Kala Z, Veselska R, Hermanova M: Clinicopathological correlations of nestin expression in surgically resectable pancreatic cancer including an analysis of perineural invasion. Journal of Gastrointestinal and Liver Diseases 20, 389-396, 2011.
  • Sana J, Zambo I, Skoda J, Neradil J, Chlapek P, Hermanova M, Mudry P, Vasikova A, Zitterbart K, Hampl A, Sterba J, Veselska R: CD133 expression and identification of CD133/nestin positive cells in rhabdomyosarcomas and rhabdomyosarcoma cell lines. Analytical Cellular Pathology 34, 303-318, 2011.
  • Krupkova Jr O, Loja T, Redova M, Neradil J, Zitterbart K, Sterba J, Veselska R: Analysis of nuclear nestin localization in cell lines derived from neurogenic tumors. Tumor Biology 32, 631-639, 2011.
  • Zitterbart K, Filkova H, Tomasikova L, Necesalova E, Zambo I, Kantorova D, Slamova I, Vranova V, Zezulkova D, Pesakova M, Pavelka Z, Veselska R, Kuglik P, Sterba J: Low-level copy number changes of MYC genes have a prognostic impact in medulloblastoma. Journal of Neurooncology 102, 25-33, 2011.
  • Nekulova M, Zitterbart K, Sterba J, Veselska R: Analysis of the intracellular localization of p73 N-terminal protein isoforms TAp73 and delta-Np73 in medulloblastoma cell lines. Journal of Molecular Histology 41, 267-275, 2010.
  • Chlapek P, Redova M, Zitterbart K, Hermanova M, Sterba J, Veselska R: Enhancement of ATRA-induced differentiation of neuroblastoma cell lines with LOX/COX inhibitors: an expression profiling study. Journal of Experimental & Clinical Cancer Research 29, Art. No. 45, 2010.
  • Krupkova Jr O, Loja T, Zambo I, Veselska R: Nestin expression in human tumors and tumor cell lines. Neoplasma 57, 291-298, 2010.
  • Veselska R, Skoda J, Loja T, Zitterbart K, Pavelka Z, Smardova J, Valaskova I, Hermanova M, Sterba J: An unusual loss of EGFR gene copy in glioblastoma multiforme in a child: a case report and analysis of a successfully derived HGG-02 cell line. Child’s Nervous System 26, 841-846, 2010.
  • Redova M, Chlapek P, Loja T, Zitterbart K, Hermanova M, Sterba J, Veselska R: Influence of LOX/COX inhibitors on cell differentiation induced by all-trans retinoic acid in neuroblastoma cell lines. International Journal of Molecular Medicine 25, 271-280, 2010.
  • Loja T, Chlapek P, Kuglik P, Pesakova M, Oltova A, Cejpek P, Veselska R: Characterization of a glioblastoma cell line showing CD133 positivity and both cytoplasmic and nuclear localization of nestin. Oncology Reports 21, 119-128, 2009.
  • Veselska R, Hermanova M, Loja T, Chlapek P, Zambo I, Vesely K, Zitterbart K, Sterba J: Nestin expression in osteosarcomas and derivation of nestin/CD133 positive osteosarcoma cell lines. BMC Cancer 8, Art. No. 300, 2008.
  • Mazanek P, Bajciova V, Sterba J, Kuglik P, Veselska R: Novinky v diagnostice a lecbe neuroblastomu. Onkologia 4, 1-5, 2008
  • Necesalova E, Vranova V, Kuglik P, Cejpek P, Jarosova M, Pesakova M, Relichova J, Veselska R: Incidence of the main genetic markers in glioblastoma multiforme is independent of tumor topology. Neoplasma 54, 212-218, 2007.
  • Vranova V, Necesalova E, Kuglik P, Cejpek P, Pesakova M, Budinska E, Relichova J, Veselska R: Screening of genomic imbalances in glioblastoma multiforme using high-resolution comparative genomic hybridization. Oncology Reports 17, 457-464, 2007.
  • Loja T, Kuglik P, Oltova A, Smuharova P, Zitterbart K, Bajciova V, Veselska R: The optimization of sample treatment for spectral karyotyping with application for human tumour cells. Cytogenetics and Genome Research 116, 186-193, 2007
  • Veselska R: Ethics of research on human embryonic stem cell lines. In: Deltas C, Kalokairinou EM, Rogge S (eds.): Progress in Science and the Danger of Hubris – Genetics, Transplantation, Stem Cell Research, pp. 101-108. Muenster: Waxmann Verlag, 2006.
  • Veselska R, Kuglik P, Cejpek P, Svachova H, Neradil J, Loja T, Relichova J: Nestin expression in cell lines derived from glioblastoma multiforme. BMC Cancer 6, Art. No. 32, 2006.
  • Necesalova E, Kuglik P, Cejpek P, Veselska R, Vranova V, Pesakova M, Relichova J: Studium polyzomie chromozomu 7, monozomie chromozomu 10, amplifikace genu EGFR a delece genu p53 u multiformniho glioblastomu pomoci metody fluorescencni in situ hybridizace (FISH). Klinicka Onkologie 19, 9-14, 2006.
  • Neradil J, Veselska R, Svoboda A: The role of actin in the apoptotic cell death of P19 embryonal carcinoma cells. International Journal of Oncology 27, 1013-1021, 2005.
  • Veselska R, Zitterbart K, Auer J, Neradil J: Differentiation of HL-60 myeloid leukemia cells induced by all-trans retinoic acid is enhanced in combination with caffeic acid. International Journal of Molecular Medicine 14, 305-310, 2004.
  • Veselska R, Kure J: Pravni a eticke aspekty zpracovani klinickych dat. Klinicka Onkologie Suppl 2004, 37-38, 2004.
  • Veselska R, Zitterbart K, Jelinkova S, Neradil J, Svoboda A: Specific cytoskeleton changes during apoptosis accompanying induced differentiation of HL-60 myeloid leukemia cells. Oncology Reports 10, 1049-1058, 2003.
  • Neradil J, Veselska R, Slanina J: UVC-protective effect of caffeic acid on the normal and transformed human skin cells in vitro. Folia Biologica 49, 197-202, 2003.
  • Koutna M, Janisch R, Veselska R: Effects of low-power laser irradiation on cell proliferation. Scripta Medica 76, 163-172, 2003.
  • Veselska R, Janisch R: Reaction of the skin fibroblast cytoskeleton to micromanipulation interventions. Journal of Structural Biology 136, 110-118, 2001.
  • Veselska R, Janisch R: Cortical actin cytoskeleton in the human oocytes: A comparison with the mouse oocytes. Scripta Medica 74, 265-272, 2001.
  • Zitterbart K, Veselska R: Effect of retinoic acid on the actin cytoskeleton in HL-60 cells. Neoplasma 48, 456-461, 2001.
  • Veselska R, Janisch R: The effect of UV irradiation on changes in cytoskeleton and viability of mouse fibroblasts L929 cell line. Scripta Medica 73, 393-408, 2000.
  • Halackova Z, Veselska R: Cytotoxicita endodontickych sealeru. Ceska stomatologie 99, 101-106, 1999.
  • Chroust K, Kuglik P, Relichova J, Holoubek I, Caslavsky J, Veselska R, Ryskova M, Benedik J: Drosophila melanogaster, Vicia faba and Arabidopsis thaliana short-term bioassays in genotoxicity evaluation air and soil samples from sites surrounding two industrial factories in the Czech Republic. Folia Biologica 43, 71-78, 1997.
  • Veselska R, Kuglik P, Relichova J: The influence of incorporated bromodeoxyuridine on mutagenicity testing by sister chromatid exchange induction in Vicia faba root-tip cells. Biologia Plantarum 37, 9-14, 1995.
  • Kuglik P, Veselska R: The use of micronucleus test to characterise adaptation of Vicia faba root tip cells to gamma-radiation. Biologia Plantarum 36, 215-220, 1994.
  • Kuglik P, Veselska R: Characterization of a cytogenetic adaptive response induced by gamma-radiation in Vicia faba root tip cells. Folia Biologica 38, 14-22, 1992.
  • Kuglik P, Slotova J, Dobricka R, Karpfel Z: Vicia faba chromosome damage induced by low doses of gamma radiation. Biologia Plantarum 32, 113-118, 1990.

TEXTBOOKS AND OTHER PUBLICATIONS:

  • Veselska R: Eticke aspekty molekularni mediciny [Ethical aspects of molecular medicine]. In: Slaby O (ed.): Molekularni medicina, Galen, Praha 2015. ISBN 9788074921216.
  • Kure J, Halamkova J, Kintrova K, Mikoskova M, Pavlik M, Slama O, Veselska R, Vysocanova P, Zvonicek V: Kapitoly z lekarske etiky. Multimedialni podpora vyuky klinickych a zdravotnickych oboru: Portal Lekarske fakulty Masarykovy univerzity, 2011.  ISSN 1801-6103.
  • Snustad DP, Simmons MJ (Translators: Relichova J, Doskar J, Fajkus J, Horin P, Knoll A, Kuglik P, Smarda J, Smardova J, Veselska R, Vyskot B): Genetika (Czech translation of the textbook). Brno: Masaryk University, MUNI Press 2009. ISBN 978-80-210-4852-2.
  • Veselska R, Smajs D, Neradil J, Matejkova P, Slaninova I, Svoboda A, Kopecka M, Gabriel M, Smarda J, Janisch R: Prakticka cviceni z biologie. Protokoly – cast II. Brno: Masarykova univerzita, 2005. ISBN 80-210-3644-3.
  • Veselska R, Gabriel M, Janisch R, Kopecka M, Neradil J, Slaninova I, Svoboda A, Smajs D, Smarda J: Prakticka cviceni z biologie. Protokoly – cast I. Brno: Masarykova univerzita, 2004. ISBN 80-210-3487-4.
  • Veselska R, Kure J (eds.): Transplantacni medicina: soucasnost a perspektivy. Sbornik k interdisciplinarni konferenci. Brno: Masarykova univerzita, 2001. ISBN 80-210-2714-2.
  • Kopecka M, Gabriel M, Svoboda A, Janisch R, Slaninova I, Veselska R, Smarda J, Chumchalova J, Holubarova A: Lekarska biologie. Cast druha – Genetika. Brno, Masarykova univerzita, 2001. ISBN 80-210-2670-7.
  • Veselska R, Kure J (eds.): Lidsky genom: vedeni, moznosti, souvislosti. Sbornik k interdisciplinarni konferenci. Brno: Masarykova univerzita, 2000. ISBN 80-210-2447-X.
  • Svoboda A, Gabriel M, Kopecka M, Janisch R, Slaninova I, Smajs D, Smarda J, Veselska R: Prakticka cviceni z biologie. Protokoly – cast I. Brno: Masarykova univerzita, 1998. ISBN 80-210-1852-6.