In the field of experimental biology, my research interests are focused on animal cell biology, especially on biology of human tumor cells. My Laboratory of Tumor Biology is a joint research unit of the Department of Experimental Biology (School of Science, Masaryk University, Brno, Czech Republic) and the Department of Pediatric Oncology (School of Medicine, Masaryk University, and University Hospital Brno, Czech Republic). Our present research topics are as follow:
- Activity of RTKs and MAPKs in relapsed and refractory pediatric solid tumors
- Cancer stem cells and mechanisms of tumorigenesis in sacromas
- Prognostic and predictive biomarkers in neurogenic solid tumors
- Mechanisms of combined anticancer therapy
Since 2015, our team joined the International Clinical Research Center, St. Anne’s University Hospital (FNUSA-ICRC). We are included in the Translational Medicine research program as the LOTR Research Group (Laboratory Oncology Translational Research).
We also thank KRTEK – the Childhood Cancer Foundation for the financial support of our research.
In the field of bioethics, I am particularly interested in ethical aspects of biomedical research, especially of human genetics and cell technologies. I am alumnus of the Bioethics Program at Union Graduate College / Mount Sinai School of Medicine (NY, USA), of the Advanced Certificate Program – Research Ethics in Central and Eastern Europe and of the Intensive Bioethics Course (Georgetown University, Washington DC, USA).