In the field of experimental biology, my research interests are focused on animal cell biology, especially on biology of human tumor cells. My Laboratory of Tumor Biology is a joint research unit of the Department of Experimental Biology (School of Science, Masaryk University, Brno, Czech Republic) and the Department of Pediatric Oncology (School of Medicine, Masaryk University, and University Hospital Brno, Czech Republic). Our present research topics are (1) activity of RTKs and MAPKs in relapsed and refractory pediatric solid tumors; (2) cancer stem cells and mechanisms of tumorigenesis in pediatric solid tumors.
In addition to the introduction and teaching of several courses on cell biology, I serve as a guarantor of the Master’s degree Study Program in Cell Biology and of the Bachelor’s degree Study program in Experimental and Molecular Biology at the School of Science, Masaryk University Brno.
In the field of bioethics, I am particularly interested in ethical aspects of biomedical research, especially of human genetics and cell technologies. I am alumnus of the Bioethics Program at Union Graduate College / Mount Sinai School of Medicine (NY, USA), of the Advanced Certificate Program – Research Ethics in Central and Eastern Europe and of the Intensive Bioethics Course (Georgetown University, Washington DC, USA).
As Professor of the Department of Medical Ethics, I introduced several courses on Bioethics for undergraduates at Masaryk University and have taught them since 2003. Furthermore, I serve as a chair of the Research Ethics Committee at Masaryk University since 2015 and thus I have deep practical experience with identification, analyzing and evaluation of emerging ethical dilemmas in various fields of science. At the national level, I was appointed as a vice-chair of the Bioethics Committee of the Research and Development Council of the Czech Government and as a member of the Ethics Committee of the Ministry of Healthcare of the Czech Republic.